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Arhgef18 - rho/rac guanine nucleotide exchange factor (GEF) 18

Alias:
A430078G23Rik
D030053O22Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
预测能够使鸟苷酸交换因子活性增强。预测参与对应力纤维组装的负调控;蛋白质定位到细胞间连接;以及调控Rho蛋白信号传导。预测在肌动蛋白细胞骨架组织、细胞形状调控以及小GTP酶介导的信号传导中起到上游或内部调控作用。预测位于细胞的顶端部分和细胞质中。预测在质膜上有活性。在大脑、真皮、表皮和肾单位中表达。这个基因的人类同源物与视网膜色素变性有关。与人类的ARHGEF18(Rho/Rac鸟苷酸交换因子18)正交。[由基因组资源联盟,2022年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
11
29
103263 bp
155.98
10
6

Arhgef18 Genetics information (+)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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