人类

CDK2 - Cyclin Dependent Kinase 2

Alias:
CDKN2
p33(CDK2)
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一个丝氨酸/苏氨酸蛋白激酶家族成员,参与细胞周期调节。编码的蛋白质是细胞周期依赖性蛋白激酶复合物的催化亚单位,可调节细胞周期的进程。在G1到S期过渡期间,该蛋白质的活性尤为重要。该蛋白质与其他复合物的亚单位结合并被其调节,包括周期蛋白A或E、CDK抑制子p21Cip1(CDKN1A)和p27Kip1(CDKN1B)。选择性剪接导致多个转录变异体。[由RefSeq,2014年3月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
4
7
5960 bp
33.93
3
--
13
71

CDK2 Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Mutation Direct
Sequence
Comparison
Al agent
Tutorials
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