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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
ARPC1B - Actin Related Protein 2/3 Complex Subunit 1B
Alias:
ARC41
IMD71
PLTEID
p40-ARC
p41-ARC
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码人类Arp2/3蛋白复合体的七个亚基之一。这个亚基是SOP2家族蛋白质的成员,与基因ARPC1A编码的蛋白质最相似。这两个蛋白质之间的相似性表明它们都可能作为人类Arp2/3复合体的p41亚基发挥作用,该复合体已被证明参与控制细胞中肌动蛋白的聚合。p41亚基可能参与组装和维护Arp2/3复合体的结构。p41亚基的多个版本可能使复合体的功能适应不同的细胞类型或发育阶段。这个蛋白质还可以通过作为Aurora A激酶的激活子和底物来参与中心体稳态。[由RefSeq,2011年3月提供]
Related ID:
NCBI:10095
ENSEMBL:ENSG00000130429
HGNC:704
UNIPROT:O15143
OMIM:604223
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
10095
2
10
20558 bp
40.95
247
3
1
10
ARPC1B Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
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Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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