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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
ARPC4 - Actin Related Protein 2/3 Complex Subunit 4
Alias:
ARC20
DEVLO
P20-ARC
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码人类Arp2/3蛋白复合物的七个亚基之一。这个复合物控制细胞中的肌动蛋白聚合,并在真核生物进化中保守。这个基因编码p20亚基,对于肌动蛋白核糖体和与F-肌动蛋白的高亲和力结合是必要的。替代剪接导致多个转录变异体。自然发生的读穿转录存在于这个基因和下游的微管蛋白酪氨酸连接酶样家族成员3(TTLL3)之间,这导致了融合蛋白的产生。[RefSeq,2010年11月提供]
Related ID:
NCBI:10093
ENSEMBL:ENSG00000241553
HGNC:707
UNIPROT:P59998
OMIM:604226
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
10093
4
6
14584 bp
19.67
3
1
5
8
ARPC4 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
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#
Transcript
Length(nt)
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CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
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Interactions
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Acting
Regulation
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Residues
Reference
Score
No data available
Related Mouse Models
Type
Name
MGI
Strain of Origin
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Mutations
No data available
Related Drugs
Name
CAS Number
Status
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Link
No data available
References Literature
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Journal
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IF
No Data Found!
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