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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
大鼠
Fbxw7 - F-box and WD repeat domain containing 7
Alias:
Fbw7
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个预测的蛋白质被认为具有多种功能,包括结合细胞周期蛋白活性、结合磷酸苏残基活性和作为泛素连接酶-底物适配器活性。它被认为参与多个过程,包括细胞蛋白质代谢过程、正调控细胞蛋白质代谢过程和正调控细胞内信号传导。这个蛋白质被认为在几个过程中起到上游或内部的作用,包括负调控RNA聚合酶II调控区序列特异性DNA结合活性、蛋白质去稳定化和血管发生。它被认为位于几个细胞组件中,包括高尔基器、核腔和细胞质核周区域。这个蛋白质被认为是一个Parkin-FBXW7-Cul1泛素连接酶复合物和SCF泛素连接酶复合物的一部分。它被认为在细胞质和细胞核中活跃。这个蛋白质的直系同源物是人类的FBXW7(F-box和WD重复结构域包含7)。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:100360914
ENSEMBL:ENSRNOG00000010889
UNIPROT:D3Z902
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
100360914
9
14
161831 bp
Unknown
16
1
Fbxw7 Genetics information (+)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
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* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Cell-specific RNA expression
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Acting
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Score
No data available
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Type
Name
MGI
Strain of Origin
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IF
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