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中文人类
SH2B3 - SH2B Adaptor Protein 3
Alias:
LNK
IDDM20
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这个基因编码SH2B适配器家族的一员，该家族参与生长因子和细胞因子受体的一系列信号传导活动。编码的蛋白质是细胞因子信号传导的关键负调控因子，并在造血中发挥关键作用。这个基因的突变与对乳糖不耐受13型的易感性和胰岛素依赖性糖尿病的易感性有关。已经发现这个基因的不同剪接转录变异体编码不同的异构体。[RefSeq，2014年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
SH2B3 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
