人类

HDAC6 - Histone Deacetylase 6

Alias:
HD6
JM21
CPBHM
PPP1R90
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
组蛋白在转录调控、细胞周期进展和发育事件中起关键作用。组蛋白的乙酰化/去乙酰化改变染色体结构并影响转录因子对DNA的访问。这个基因编码的蛋白质属于组蛋白去乙酰酶/acuc/apha家族的II类。它包含两个催化域的内部重复,这些域似乎彼此独立地发挥作用。这个蛋白质具有组蛋白去乙酰酶活性并抑制转录。[由RefSeq,2008年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
13
29
23585 bp
131.42
72
1
11
30

HDAC6 Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Comparison
Al agent
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