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Pcsk9 - proprotein convertase subtilisin/kexin type 9

Alias:
FH3
PC9
Narc1
HCHOLA3
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码一个蛋白质,具有激活载脂蛋白结合活性、脂蛋白颗粒结合活性和低密度脂蛋白颗粒受体结合活性。该蛋白质参与几个过程,包括对胰岛素刺激的细胞反应、对饥饿的细胞反应和神经元凋亡过程的调节。它位于COPII包被的内质网到高尔基体运输囊泡、内质网和细胞外空间。它在消化系统、小脑、生殖泌尿系统、肝脏和端脑等几个结构中表达。这个基因的人类同源物与家族性高胆固醇血症和低β-脂蛋白血症有关。它与人类的PCSK9(前蛋白转化酶亚基9)同源。[由基因组资源联盟,2022年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
1
12
21992 bp
74.82
15
9

Pcsk9 Genetics information (-)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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