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中文人类
TANK - TRAF Family Member Associated NFKB Activator
Alias:
ITRAF
TRAF2
I-TRAF
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肿瘤坏死因子受体相关因子（TRAF）家族的蛋白质与肿瘤坏死因子受体超家族的成员结合并传递信号。这个基因编码的蛋白质存在于细胞质中，可以与TRAF1、TRAF2或TRAF3结合，从而通过将TRAFs隐藏在细胞质中的潜伏状态中来抑制TRAF的功能。例如，这个基因编码的蛋白质可以阻断TRAF2与LMP1（EB病毒转化蛋白）的结合，并抑制LMP1介导的NF-kappa-B激活。已经在这个基因中发现了编码不同异构体的三种可变剪接转录变异体。[RefSeq，2010年11月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
TANK Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
