人类

NAALAD2 - N-acetylated Alpha-linked Acidic Dipeptidase 2

Alias:
GCP3
GCPIII
GPCIII
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因是N-乙酰化α连接酸性二肽酶(NAALADase)基因家族的成员。这个家族的代表成员是编码人类前列腺特异性膜抗原(PSM)的基因,它是前列腺癌的标志物,并被首先证明具有NAALADase活性。NAALADase切割N-乙酰-L-天冬氨酸-L-谷氨酸(NAAG),这是一种在中枢神经系统和外周表达的神经营养物质,被认为具有神经递质功能。这个基因的产物是一种II型整合膜蛋白。这个基因瞬时转染到哺乳动物细胞中,赋予其NAALADase和二肽肽酶IV活性。这个基因在卵巢、睾丸以及大脑特定点位中高表达。已经发现这个基因有两个编码不同异型的转录变异体。[由RefSeq,2014年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
6
19
61196 bp
83.59
32
--
3
5

NAALAD2 Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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