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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
NAALAD2 - N-acetylated Alpha-linked Acidic Dipeptidase 2
Alias:
GCP3
GCPIII
GPCIII
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因是N-乙酰化α连接酸性二肽酶(NAALADase)基因家族的成员。这个家族的代表成员是编码人类前列腺特异性膜抗原(PSM)的基因,它是前列腺癌的标志物,并被首先证明具有NAALADase活性。NAALADase切割N-乙酰-L-天冬氨酸-L-谷氨酸(NAAG),这是一种在中枢神经系统和外周表达的神经营养物质,被认为具有神经递质功能。这个基因的产物是一种II型整合膜蛋白。这个基因瞬时转染到哺乳动物细胞中,赋予其NAALADase和二肽肽酶IV活性。这个基因在卵巢、睾丸以及大脑特定点位中高表达。已经发现这个基因有两个编码不同异型的转录变异体。[由RefSeq,2014年7月提供]
Related ID:
NCBI:10003
ENSEMBL:ENSG00000077616
HGNC:14526
UNIPROT:Q9Y3Q0
OMIM:611636
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
10003
6
19
61196 bp
83.59
32
--
3
5
NAALAD2 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
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* This data comes from NCBI.
Gene Expression
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