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中文人类
ADA - Adenosine Deaminase
Alias:
ADA1
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这个基因编码一种酶，在嘌呤分解代谢途径中催化腺苷水解成肌苷。这个基因的各种突变与人类免疫功能受损相关疾病如严重联合免疫缺陷病（SCID）有关，这是由于ADA酶缺陷引起的。在ADA缺陷的个体中，T、B和NK淋巴细胞显著减少，从而导致体液免疫和细胞免疫的缺乏。相反，这种酶的升高水平与先天性溶血性贫血有关。[RefSeq, 2019年9月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
ADA Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
