Webb-Dattani Syndrome, is also known as hypothalamo-pituitary-frontotemporal hypoplasia with visual and renal anomalies, and has symptoms including muscle spasticity and seizures. An important gene associated with Webb-Dattani Syndrome is ARNT2 (Aryl Hydrocarbon Receptor Nuclear Translocator 2). Affiliated tissues include pituitary and temporal lobe, and related phenotypes are spasticity and blindness