Villonodular Synovitis

Villonodular Synovitis, also known as pigmented villonodular synovitis, is related to tenosynovial giant cell tumor and pigmented villonodular synovitis, and has symptoms including pain, arthralgia and other symptoms referable to joint. An important gene associated with Villonodular Synovitis is SOS1 (SOS Ras/Rac Guanine Nucleotide Exchange Factor 1), and among its related pathways/superpathways are Innate Immune System and Immune response IL-23 signaling pathway. The drugs Antibodies and Immunoglobulins have been mentioned in the context of this disorder. Affiliated tissues include bone and lung, and related phenotypes are Increased shRNA abundance (Z-score > 2) and muscle