Ulcerative Colitis (UC)

Ulcerative Colitis, also known as left sided ulcerative colitis, is related to inflammatory bowel disease 1 and proctitis, and has symptoms including abdominal pain, constipation and diarrhea. An important gene associated with Ulcerative Colitis is H19 (H19 Imprinted Maternally Expressed Transcript), and among its related pathways/superpathways are Innate Immune System and MIF Mediated Glucocorticoid Regulation. The drugs Sodium citrate and Hydrocortisone have been mentioned in the context of this disorder. Affiliated tissues include Bone, colon and bone marrow, and related phenotypes are Synthetic lethal with MLN4924 (a NAE inhibitor) and homeostasis/metabolism