Toxic Megacolon

Toxic Megacolon, also known as megacolon, toxic, is related to inflammatory bowel disease 1 and intestinal pseudo-obstruction. An important gene associated with Toxic Megacolon is ATP12A (ATPase H+/K+ Transporting Non-Gastric Alpha2 Subunit), and among its related pathways/superpathways are Innate Immune System and Cytokine Signaling in Immune system. Affiliated tissues include colon and smooth muscle, and related phenotypes are homeostasis/metabolism and growth/size/body region