Tropical Spastic Paraparesis (TSP)

Tropical Spastic Paraparesis, also known as human t-lymphotropic virus type i-associated myelopathy/tropical spastic paraparesis, is related to myelopathy, htlv-1-associated and spinal cord disease. An important gene associated with Tropical Spastic Paraparesis is CNTN2 (Contactin 2), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Zidovudine and Lamivudine have been mentioned in the context of this disorder. Affiliated tissues include spinal cord and breast, and related phenotypes are growth/size/body region and homeostasis/metabolism