Transposition of the Great Arteries (TGA)

Transposition of the Great Arteries, also known as transposition of the great vessels, is related to transposition of the great arteries, dextro-looped and double outlet right ventricle. An important gene associated with Transposition of the Great Arteries is GATA4 (GATA Binding Protein 4), and among its related pathways/superpathways are Embryonic and Induced Pluripotent Stem Cells and Lineage-specific Markers and Endoderm differentiation. The drugs Mechlorethamine and Eplerenone have been mentioned in the context of this disorder. Affiliated tissues include heart and skin.