Tn Polyagglutination Syndrome (TNPS)

Tn Polyagglutination Syndrome, also known as galactosyltransferase deficiency, is related to ehlers-danlos syndrome, spondylodysplastic type, 1 and congenital disorder of glycosylation, type iid. An important gene associated with Tn Polyagglutination Syndrome is C1GALT1C1 (C1GALT1 Specific Chaperone 1), and among its related pathways/superpathways are Diseases of glycosylation and O-linked glycosylation of mucins. Affiliated tissues include t cells and colon, and related phenotypes are autoimmunity and abnormal erythrocyte morphology