Thrombophilia Due to Thrombin Defect (THPH1)

凝血酶缺陷引起血栓形成倾向(来自ICD-11)

别称:

Venous Thromboembolism

Venous Thrombosis

Thromboembolism

Venous Thromboembolism, Susceptibility to

Thrombophilia Due to Factor 2 Defect

Thromboembolism, Susceptibility to

Thph1

Venous Thrombosis, Protection Against

Venous Thrombosis, Susceptibility to

Prothrombin-Related Thrombophilia

Thrombophilia 1 Due to Thrombin Defect

Thrombophilia,due to Thrombin Defect

Hyperprothrombinemia

加入收藏

基础信息

疾病表征

基因 & 突变

靶点药物

疾病模型

文献报道

凝血因子缺陷引起的血栓性倾向，也称为静脉血栓栓塞，与凝血酶原血栓性倾向和同型半胱氨酸血症有关。与凝血因子缺陷引起的血栓性倾向有关的重要基因是MTHFR（甲硫氨酸四氢叶酸还原酶），其相关通路/超级通路包括细胞质钙离子升高的反应和补体通路。在该疾病的背景下提到了Dydrogesterone和Nadroparin这两种药物。相关组织包括肺和脊髓，相关表型为稳态/代谢和神经系统。

查看原文参与反馈