Tuberous Sclerosis

Tuberous Sclerosis, also known as bourneville's disease, is related to tuberous sclerosis 1 and polycystic kidney disease, infantile severe, with tuberous sclerosis, and has symptoms including back pain, headache and pain. An important gene associated with Tuberous Sclerosis is TSC2 (TSC Complex Subunit 2), and among its related pathways/superpathways are ERK Signaling and Signal Transduction. The drugs Doxycycline and Cannabidiol have been mentioned in the context of this disorder. Affiliated tissues include kidney and skin, and related phenotypes are Decreased viability and Increased shRNA abundance (Z-score > 2)