Stiff Skin Syndrome (SSKS)

Stiff Skin Syndrome, also known as ssks, is related to systemic scleroderma and localized scleroderma. An important gene associated with Stiff Skin Syndrome is FBN1 (Fibrillin 1), and among its related pathways/superpathways are ERK Signaling and PAK Pathway. Affiliated tissues include skin and eye, and related phenotypes are limitation of joint mobility and lack of skin elasticity