Spastic Paraplegia 2, X-Linked (SPG2)

Spastic Paraplegia 2, X-Linked, also known as spg2, is related to pelizaeus-merzbacher disease and leukodystrophy, and has symptoms including ataxia and cerebellar signs. An important gene associated with Spastic Paraplegia 2, X-Linked is PLP1 (Proteolipid Protein 1). Affiliated tissues include spinal cord and eye, and related phenotypes are spasticity and hyperreflexia