Spastic Paraplegia 11

Spastic Paraplegia 11, also known as autosomal recessive spastic paraplegia with mental impairment and thin corpus callosum, is related to spastic paraplegia 11, autosomal recessive and hereditary spastic paraplegia, and has symptoms including ataxia, urgency of micturition and abnormal pyramidal signs. An important gene associated with Spastic Paraplegia 11 is SPG11 (SPG11 Vesicle Trafficking Associated, Spatacsin). The drugs Miglustat and Glycoside Hydrolase Inhibitors have been mentioned in the context of this disorder. Affiliated tissues include spinal cord and brain.