Sporadic Hemiplegic Migraine, also known as non-familial hemiplegic migraine, is related to familial or sporadic hemiplegic migraine and migraine with or without aura 1. An important gene associated with Sporadic Hemiplegic Migraine is CACNA1A (Calcium Voltage-Gated Channel Subunit Alpha1 A). Affiliated tissues include eye and brain.