Sinoatrial Node Disease

Sinoatrial Node Disease, also known as sinus node dysfunction, is related to cardiac arrhythmia, ankyrin-b-related and sick sinus syndrome. An important gene associated with Sinoatrial Node Disease is SCN5A (Sodium Voltage-Gated Channel Alpha Subunit 5), and among its related pathways/superpathways are G-Beta Gamma Signaling and Cardiac conduction. The drugs Propafenone and Digoxin have been mentioned in the context of this disorder. Affiliated tissues include heart and atrioventricular node, and related phenotypes are muscle and homeostasis/metabolism