Scleroderma, Familial Progressive

Scleroderma, Familial Progressive, also known as systemic sclerosis, is related to diffuse scleroderma and raynaud disease, and has symptoms including exanthema, pruritus and hidebound skin. An important gene associated with Scleroderma, Familial Progressive is CCN2 (Cellular Communication Network Factor 2), and among its related pathways/superpathways are Phospholipase-C Pathway and MET promotes cell motility. The drugs Sodium citrate and Ropivacaine have been mentioned in the context of this disorder. Affiliated tissues include skin and lung, and related phenotypes are arthralgia and myalgia