Retinal Dystrophy, Optic Nerve Edema, Splenomegaly, Anhidrosis, and Migraine Headache Syndrome (ROSAH)

Retinal Dystrophy, Optic Nerve Edema, Splenomegaly, Anhidrosis, and Migraine Headache Syndrome, also known as optic nerve edema-splenomegaly syndrome, is related to anhidrosis and fundus dystrophy. An important gene associated with Retinal Dystrophy, Optic Nerve Edema, Splenomegaly, Anhidrosis, and Migraine Headache Syndrome is ALPK1 (Alpha Kinase 1). Affiliated tissues include eye and bone, and related phenotypes are anhidrosis and splenomegaly