Refractory Anemia

难治性贫血(来自翻译大模型)

别称:

Rars-T [refractory Anaemia with Ringed Sideroblasts Associated with Marked Thrombocytosis]

Refractory Anemia, Without Ringed Sideroblasts, Without Excess Blasts

Raeb - [refractory Anaemia with Excess Blasts] Nos

Raeb - [refractory Anaemia with Excess Blasts]

Acquired Idiopathic Sideroblastic Anaemia

Refractory Anaemia Without Sideroblasts

Primary Acquired Sideroblastic Anaemia

Refractory Anaemia with Excess Blasts

Refractory Anaemia with Sideroblasts

Refractory Sideroblastic Anaemia

Refractory Anemias

Anemia Refractory

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基础信息

疾病表征

基因 & 突变

靶点药物

疾病模型

文献报道

难治性贫血，又称为环状铁粒幼红细胞性难治性贫血伴明显血小板增多症，与获得性特发性铁粒幼红细胞性贫血和难治性贫血伴过多原始细胞有关。与难治性贫血相关的基因是TET2（Tet甲基胞嘧啶氧化酶2），其相关通路/超级通路包括造血干细胞和特异性标记物。在该疾病的背景下提到了多巴胺和柠檬酸镁。附属组织包括骨髓和骨，相关表型为骨髓增生异常和生产不足性贫血。

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