Pitt-Hopkins Syndrome (PTHS)

Pitt-Hopkins Syndrome, also known as pths, is related to pitt-hopkins-like syndrome 1 and pitt-hopkins-like syndrome 2, and has symptoms including constipation, seizures and nasal flaring. An important gene associated with Pitt-Hopkins Syndrome is TCF4 (Transcription Factor 4), and among its related pathways/superpathways are MECP2 and associated Rett syndrome and Myogenesis. The drugs Magnesium citrate and Sodium citrate have been mentioned in the context of this disorder. Affiliated tissues include testes and brain, and related phenotypes are intellectual disability and failure to thrive