Postaxial Acrofacial Dysostosis (POADS)

Postaxial Acrofacial Dysostosis, also known as Miller syndrome, is related to dysostosis and acrofacial dysostosis. An important gene associated with Postaxial Acrofacial Dysostosis is DHODH (Dihydroorotate Dehydrogenase (Quinone)), and among its related pathways/superpathways are Pyrimidine metabolism and Pyrimidine biosynthesis. The drugs Cimetidine and Pharmaceutical Solutions have been mentioned in the context of this disorder. Affiliated tissues include eye and bone, and related phenotypes are microtia and micrognathia. （Postaxial Acrofacial Dysostosis，也称为Miller syndrome，与dysostosis和acrofacial dysostosis有关。与Postaxial Acrofacial Dysostosis相关的基因是DHODH（Dihydroorotate Dehydrogenase（Quinone）），其相关途径/超级途径包括嘧啶代谢和嘧啶生物合成。在该疾病的背景下，Cimetidine和Pharmaceutical Solutions已被提及。附属组织包括眼睛和骨骼，相关表型为microtia和micrognathia。）