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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
非罕见病
Pustulosis of Palm and Sole
Alias:
Psoriasis
Pustular Psoriasis of the Palms and/or Soles
Acrodermatitis Continua of Hallopeau
Generalized Pustular Psoriasis
Pustulosis of Palms and Soles
Palmoplantar Pustulosis
Acropustulosis
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基础信息
疾病表征
基因 & 突变
靶点药物
疾病模型
文献报道
掌跖脓疱病,又称银屑病,与牙周炎、侵袭性银屑病和银屑病1有关,症状包括皮疹、瘙痒和银屑病样皮疹。掌跖脓疱病相关的重要基因是IL36RN(白细胞介素36受体拮抗剂),其相关通路/超级通路包括先天免疫系统和MIF介导的糖皮质激素调节。在该疾病的背景下,已提到的药物有维多利珠单抗和二甲砜。相关组织包括皮肤和肝脏,相关表型为稳态/代谢和免疫系统。
Related ID:
MALACARDS:PST011
MESH:D011565
Basic Information
Inheritance
Age of Onset
Prevalence
Related Gene
Related Mouse Models
Reference
MALACARDS
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未知
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18
171
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PST011
Medical Symptom
#
Categorization
Description
HPO Frequency
Orphanet Frequency
HPO Source Accession
No data available
Gene & Mutation
#
Gene
Function
Score
Mutations
No data available
Related Drugs
Name
CAS Number
Status
Phase
No data available
Disease Model
Category
Name
MGI
Related Gene
Strain of Origin
Publications
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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