Pervasive Developmental Disorder, also known as pervasive development disorder, is related to autism spectrum disorder and autism, and has symptoms including sleep disturbances, photophobia and personality changes. An important gene associated with Pervasive Developmental Disorder is SPTBN1 (Spectrin Beta, Non-Erythrocytic 1), and among its related pathways/superpathways are Transmission across Chemical Synapses and Neuroscience. The drugs Oxytocin and Metformin have been mentioned in the context of this disorder. Affiliated tissues include brain and bone marrow, and related phenotypes are nervous system and growth/size/body region