Proteasome-Associated Autoinflammatory Syndrome (PRAAS)

Proteasome-Associated Autoinflammatory Syndrome, also known as autoinflammation-lipodystrophy-dermatosis syndrome, is related to proteasome-associated autoinflammatory syndrome 1 and proteasome-associated autoinflammatory syndrome 3. An important gene associated with Proteasome-Associated Autoinflammatory Syndrome is PSMB8 (Proteasome 20S Subunit Beta 8), and among its related pathways/superpathways are Nervous system development and TGF-Beta Pathway. Affiliated tissues include skin and bone, and related phenotypes are Synthetic lethal with gemcitabine and Increased homologous recombination repair frequency