Pure Autonomic Failure (PAF)

Pure Autonomic Failure, also known as idiopathic orthostatic hypotension, is related to multiple system atrophy 1 and dysautonomia. An important gene associated with Pure Autonomic Failure is DBH (Dopamine Beta-Hydroxylase), and among its related pathways/superpathways is Neuroscience. The drugs Naloxone and Diazoxide have been mentioned in the context of this disorder. Affiliated tissues include spinal cord and brain, and related phenotypes are abnormal autonomic nervous system physiology and orthostatic hypotension