Prothrombin Deficiency

Prothrombin Deficiency, also known as factor ii deficiency, is related to prothrombin deficiency, congenital and infective endocarditis. An important gene associated with Prothrombin Deficiency is F2 (Coagulation Factor II, Thrombin), and among its related pathways/superpathways are Metabolism of proteins and Response to elevated platelet cytosolic Ca2+. The drugs Warfarin and Anticoagulants have been mentioned in the context of this disorder. Affiliated tissues include liver and brain, and related phenotypes are prolonged prothrombin time and prolonged partial thromboplastin time