Protein C Deficiency

Protein C Deficiency, also known as congenital thrombotic disease, due to protein c deficiency, is related to budd-chiari syndrome and vitamin k deficiency bleeding. An important gene associated with Protein C Deficiency is PROC (Protein C, Inactivator Of Coagulation Factors Va And VIIIa), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Collagen chain trimerization. The drugs Protein C and Anticoagulants have been mentioned in the context of this disorder. Affiliated tissues include skin and liver, and related phenotypes are Synthetic lethal with vaccinia virus (VACV) infection and homeostasis/metabolism