Perrault Syndrome 3, also known as prlts3, is related to perrault syndrome and premature menopause. An important gene associated with Perrault Syndrome 3 is CLPP (Caseinolytic Mitochondrial Matrix Peptidase Proteolytic Subunit). Affiliated tissues include uterus and ovary, and related phenotypes are sensorineural hearing impairment and elevated circulating follicle stimulating hormone level