Peeling Skin with Leukonychia, Acral Punctate Keratoses, Cheilitis, and Knuckle Pads (PLACK)

Peeling Skin with Leukonychia, Acral Punctate Keratoses, Cheilitis, and Knuckle Pads, also known as plack, is related to cheilitis and peeling skin syndrome. An important gene associated with Peeling Skin with Leukonychia, Acral Punctate Keratoses, Cheilitis, and Knuckle Pads is CAST (Calpastatin). Affiliated tissues include skin and tongue, and related phenotypes are hyperkeratosis and abnormal blistering of the skin