Pulmonary Alveolar Proteinosis, Acquired, also known as autoimmune pulmonary alveolar proteinosis, is related to pulmonary alveolar proteinosis and sleep apnea, and has symptoms including chest pain, coughing and hemoptysis. An important gene associated with Pulmonary Alveolar Proteinosis, Acquired is HLA-DRB1 (Major Histocompatibility Complex, Class II, DR Beta 1). The drugs Oxycodone and Guaifenesin have been mentioned in the context of this disorder. Affiliated tissues include lung and liver, and related phenotypes are intraalveolar phospholipid accumulation and dyspnea