Plummer's Disease

Plummer's Disease, also known as toxic nodular goiter, is related to goiter, multinodular 1, with or without sertoli-leydig cell tumors and adenoma. An important gene associated with Plummer's Disease is TG (Thyroglobulin), and among its related pathways/superpathways are Cell adhesion_Cell-matrix glycoconjugates and Thromboxane A2 receptor signaling. The drugs Iodine and Cadexomer iodine have been mentioned in the context of this disorder. Affiliated tissues include thyroid and bone, and related phenotypes are hearing/vestibular/ear and endocrine/exocrine gland