Otopalatodigital Syndrome, Type Ii (OPD2)

Otopalatodigital Syndrome, Type II, also known as otopalatodigital syndrome type 2, is related to terminal osseous dysplasia and frontometaphyseal dysplasia. An important gene associated with Otopalatodigital Syndrome, Type II is FLNA (Filamin A), and among its related pathways/superpathways are Cytoskeletal Signaling and MAPK signaling pathway. The drugs Valproic acid and Neurotransmitter Agents have been mentioned in the context of this disorder. Affiliated tissues include bone and heart, and related phenotypes are hearing impairment and skeletal dysplasia.