Osteopathia Striata with Cranial Sclerosis (OSCS)

Osteopathia Striata with Cranial Sclerosis, also known as hyperostosis generalisata with striations, is related to craniometadiaphyseal osteosclerosis with hip dysplasia and cleft palate, isolated, and has symptoms including apnea and headache. An important gene associated with Osteopathia Striata with Cranial Sclerosis is AMER1 (APC Membrane Recruitment Protein 1). Affiliated tissues include bone and heart, and related phenotypes are thickened calvaria and increased bone mineral density