Osteomalacia

Osteomalacia, also known as adult rickets, is related to hypophosphatasia, adult and fanconi renotubular syndrome 2. An important gene associated with Osteomalacia is DMP1 (Dentin Matrix Acidic Phosphoprotein 1), and among its related pathways/superpathways are Endochondral ossification with skeletal dysplasias and Vitamin D receptor pathway. The drugs Parathyroid hormone and Cholecalciferol have been mentioned in the context of this disorder. Affiliated tissues include bone and kidney, and related phenotypes are homeostasis/metabolism and renal/urinary system