Neurodegeneration, Childhood-Onset, with Brain Atrophy (CONDBA)

Neurodegeneration, Childhood-Onset, with Brain Atrophy, also known as childhood-onset motor and cognitive regression syndrome with extrapyramidal movement disorder, is related to rare syndromic intellectual disability. An important gene associated with Neurodegeneration, Childhood-Onset, with Brain Atrophy is UBTF (Upstream Binding Transcription Factor). Affiliated tissues include brain, and related phenotypes are abnormal pyramidal sign and dysarthria