Noonan Syndrome and Noonan-Related Syndrome

Noonan Syndrome and Noonan-Related Syndrome is related to spitz nevus and woolly hair nevus. An important gene associated with Noonan Syndrome and Noonan-Related Syndrome is BRAF (B-Raf Proto-Oncogene, Serine/Threonine Kinase), and among its related pathways/superpathways are Infectious disease and ERK Signaling. Affiliated tissues include cortex and heart, and related phenotypes are Decreased viability and Increased shRNA abundance (Z-score > 2)