Nicolaides-Baraitser Syndrome (NCBRS)

Nicolaides-Baraitser Syndrome, also known as ncbrs, is related to clark-baraitser syndrome and familial isolated trichomegaly. An important gene associated with Nicolaides-Baraitser Syndrome is SMARCA2 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily A, Member 2), and among its related pathways/superpathways are Thermogenesis and Transcription Ligand-dependent activation of the ESR1/SP pathway. Affiliated tissues include skin and testes, and related phenotypes are intellectual disability and aphasia