Mental Retardation with Spastic Paraplegia and Palmoplantar Hyperkeratosis

Mental Retardation with Spastic Paraplegia and Palmoplantar Hyperkeratosis, also known as paraplegia-intellectual disability-hyperkeratosis syndrome, is related to paraplegia-intellectual disability-hyperkeratosis syndrome, and has symptoms including tremor of hands An important gene associated with Mental Retardation with Spastic Paraplegia and Palmoplantar Hyperkeratosis is IQSEC2 (IQ Motif And Sec7 Domain ArfGEF 2). Related phenotypes are intellectual disability and tremor