Malignant Fibrous Histiocytoma (MFH)

Malignant Fibrous Histiocytoma, also known as histiocytoma, malignant fibrous, is related to cutaneous fibrous histiocytoma and myxofibrosarcoma. An important gene associated with Malignant Fibrous Histiocytoma is MFHAS1 (Multifunctional ROCO Family Signaling Regulator 1), and among its related pathways/superpathways are Cytoskeletal Signaling and DNA Damage. The drugs Dactinomycin and Etoposide have been mentioned in the context of this disorder. Affiliated tissues include bone and endothelial, and related phenotypes are Reduced mammosphere formation and Synthetic lethal with vaccinia virus (VACV) infection