Melioidosis, also known as acute and fulminating melioidosis, is related to glanders and septic arthritis, and has symptoms including fever, respiratory distress and chest pain. An important gene associated with Melioidosis is TLR5 (Toll Like Receptor 5), and among its related pathways/superpathways are Infectious disease and Innate Immune System. The drugs Sulfamethoxazole and Trimethoprim have been mentioned in the context of this disorder. Affiliated tissues include lung and liver, and related phenotypes are fever and sepsis