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中文Mediastinal Gray Zone Lymphoma
Alias:
Mediastinal B-Cell Lymphoma, Unclassifiable, with Features Intermediate Between Diffuse Large B-Cell Lymphoma and Classical Hodgkin Lymphoma
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纵隔灰色区淋巴瘤，又称纵隔B细胞淋巴瘤，未分类，具有弥漫性大B细胞淋巴瘤和经典霍奇金淋巴瘤之间的特征，与淋巴瘤、霍奇金、经典和B细胞淋巴瘤有关。与纵隔灰色区淋巴瘤相关的重要基因是TNFRSF8（肿瘤坏死因子受体超家族成员8），其相关通路/超通路包括NF-κB信号通路和SARS-CoV-2介导的外周和滤泡B细胞激活。相关表型是shRNA丰度增加（Z-score>2）和免疫系统。
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